Janis Spigulis
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Professor, Department of Physics at University of Latvia Head, Biophotonics
Laboratory of IAPS Address: E-mail: janis.spigulis[at]lu.lv Telephone
/ fax: +371 67228249 |
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With background in atomic spectroscopy,
optoelectronics and fibre optics, over the last decade I am mostly involved in biophotonics research. We develop novel optical methods and devices for
non-invasive diagnostics and monitoring of human health condition.
Spectral, temporal and imaging analysis of optical signals from in-vivo skin
may ensure quantitave assessment of cardio-vascular
state, skin blood micro-circulation, skin pigmentation and various skin
malformations. The techniques developed in laboratory and evaluated in clinical
studies are photoplethysmography (PPG), fluorescence,
diffuse reflectance spectroscopy and multi-spectral imaging. The expected
outcomes of our research are advanced clinical technologies, such as:
ü Fast detection of leg stenosis by
bilateral PPG;
ü Remote cardiovascular monitoring by
embedded wireless PPG sensors;
ü Remote skin blood perfusion control
during anaesthesia by PPG imaging;
ü Remote skin chromophore
mapping by multi-spectral imaging analysis;
ü Remote skin melanoma detection by chromophore correlation analysis and parametric imaging;
ü Improved skin laser safety standards
with respect to skin “photo-memory” at low power irradiation.
The recent
developments in these areas are reviewed here.